局部症狀：異常腫塊或腫脹（腫瘤），出血，疼痛和潰瘍。因為腫瘤壓迫周遭組織所引起的症狀，如黃疸。患者通常在早期就可以通过肉眼辨认出黑色素瘤。如果它还没有转移至皮肤以外的部位，医生可以手术切除并治愈黑色素瘤。止痛藥，如嗎啡、羥可酮（英语�

ADR has historically been divided involving ways of resolving disputes beyond official judicial mechanisms and informal approaches attached to Formal judicial mechanisms. Regardless of whether They can be Component of an overarching continuing, the mechanisms are normally equivalent. You will find four typical lessons of ADR: negotiation, mediation